Successful treatment of pulmonary zygomycosis in two transplant recipients with liposomal amphotericin B and partial surgical resection followed by posaconazole.

نویسندگان

  • David T Cooke
  • Francis D Pagani
  • Daniel R Kaul
  • Kenneth R Cooke
  • Christine L Lau
  • James Riddell
چکیده

David T. Cooke, Francis D. Pagani, Daniel R. Kaul, Kenneth R. Cooke, Christine L. Lau and James Riddell IV Division of Cardiothoracic Surgery, University of California, Davis Medical Center, Davis, CA, USA, Section of Cardiac Surgery, University of Michigan Medical Center, Ann Arbor, MI, USA, Division of Infectious Diseases, University of Michigan Medical Center, Ann Arbor, MI, USA, Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, OH, USA and Division of Thoracic and Cardiovascular Surgery, University of Virginia, Charlotte, VA, USA

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منابع مشابه

Postrenal transplant renopulmonary zygomycosis with vascular aneurysms responded to surgical treatment and salvage therapy with posaconazole after failure to respond to liposomal amphotericin

BACKGROUND Zygomycosis is a difficult to treat and frequently fatal infection affecting immunocompromised and (rarely) immunocompetent patients. It requires a multifaceted approach involving elimination of predisposing factors, surgical debridement, and antifungal therapy. CASE REPORT We report the case of a postrenal transplant patient who developed disseminated zygomycosis with vascular ane...

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Treatment of zygomycosis: current and new options.

Zygomycosis is a frequently lethal invasive infection in high-risk patients such as the immunocompromised [especially haematopoietic stem cell transplant (HSCT) recipients] and patients with type 2 diabetes mellitus. However, zygomycosis has also been reported in individuals without known risk factors. The causative fungi are members of the order Mucorales and individual species within this gro...

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Surgical resection and liposomal amphotericin B to treat cavitary pulmonary zygomycosis in a patient with diabetes.

We describe a 24-year-old man with type 1 diabetes mellitus and a cavitary lesion in the right upper lobe, caused by a zygomycete. Surgical resection plus liposomal amphotericin B therapy was successful. We discuss predisposing condition, clinical findings, diagnosis, and treatment of pulmonary zygomycosis.

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Mucormycosis in renal transplant recipients: review of 174 reported cases

BACKGROUND Mucormycosis is a highly lethal fungal infection especially in immunocompromised individuals. METHODS In order to review the epidemiology, diagnosis, and treatment of mucormycosis in renal transplant recipients we searched publications of mucormycosis cases in renal transplant recipients in PUBMED database up to December 2015. RESULTS A total of 174 cases in renal transplant reci...

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Treatment of Cerebral Mucormycosis with Prolonged Liposomal Amphotericin B (>1000 days)

Mucormycosis is a rare but invasive and potentially lethal infection caused by ubiquitous fungi of the order Mucorales. The primary mode of infection is inhalation of fungal spores. Rhinocerebral and pulmonary infections are most common, however, other organ systems including the central nervous system can be affected, presumably by occult fungemia. We describe the prolonged treatment course (>...

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عنوان ژورنال:
  • Mycoses

دوره 53 2  شماره 

صفحات  -

تاریخ انتشار 2010